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Doctors' Answers to "Frequently Asked Questions" - Trilafon
Answer: Fire your consultant. Sounds like their is probably no current contraindication to the tricyclics. The ekg problems are usually dose dependent and you don't mention his dosage. High doses could be a problem," average" doses are probably ok unless he has a documented problem with arrthymias.
Answer: Trilafon is the brand name for perphenazine. This is a drug which is used to treat different types of psychotic behavior. It is believed to work in the central thalamus or hypothalamus. It is a effective drug; but, like many of this class can produce tardive dyskinesia over time. This is a syndrome of uncontrollable grimaces and tics of the facial muscles. Once present, it will not abate and is currently untreatable. Occasional cases of neuroleptic malignant syndrome are also seen. This results in sustained rise in temperature, muscle rigidity and cardiac arrhythmiaís.