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Doctors' Answers to "Frequently Asked Questions" - Periactin
Answer: Cyproheptadine is sold under the brand name periactin. This is a H1 blocker as well as a 5HT blocker. It's usual use is for treatment of skin allergies, especially cold reactions. It has been used to treat sexual dysfunction on the SSRI antidepressants. It is also used in migraine prophylaxis and treatment of hypermotility syndromes of the gi tract. One of the side effects of chronic use(migraines and the like) was observed to be weight gain. So, some patients gain weight. The mechanism of this is not clear, but may be through blockage of growth hormone sites. There is no severe long term problems reported to date. You can get more specific action from the company Merck 800-672-2568.
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