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Doctors' Answers to "Frequently Asked Questions" - Oruvail
Oruvail [posted 8/11/98]
Answer: Oruvail is a non-steroidal anti-inflammatory. In general, the side effects of this class of drug are GI. Diarrhea, nausea, gastritis, ulcers, etc. There is a long list of possible other problems but, 95% will be GI. Foods that increase gastric inflammation, alcohol, aspirin, etc. should be avoided.
Oruvail and Elevated Blood Pressure [posted 7/30/98]
Answer: Any of the non-steroidal anti-inflammatories can cause sodium retention and elevated blood pressure. This effect would cease within a few days after discontinuance of the drug. Occasional patients have decreased renal function on these drugs which could affect blood pressure as well, but is much less common.
Arthrotec and Oruvail
Answer: Both are non-steroidal anti-inflammatories. They are from different classes and might have different effects in different people. But, from a practical point of view they usually work about the same with the same side effects (GI usually). Common side effects are gastritis, diarrhea, fluid retention, ulcers, decreased clotting ability.
Answer: If your wife is depressed on DayPro, she will likely be depressed on Oruvail since they are from the same class of drugs. However, the only way to find out is to try it and see. DayPro and that class of drugs are not notorious for producing depression. I'd ensure that the DayPro is the culprit.