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Doctors' Answers to "Frequently Asked Questions" - Axid


These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

Breast Enlargement
Question: I was prescribed AXID 150mg at first and now axid 300mg. I found the list of side effects of this drug on the internet. One of them is Breast enlargement. I want to know what is the percentage of patients who actually get this side effect and if this side effect stops after I finish taking this drug. My breast are already too large, I'm afraid they'll get bigger.

Answer: I've never had a female or male patient complain of this problem. The risk in men(where it is usually noticed first) is about 1% according to the research. The incidence in women is less clear. I'd try it and see-I rarely see this and I must have 1000 or so patients on this or something equivalent.

Axid & Propulsid
Question: Two weeks ago I started having heartburn daily, so my doctor prescribed AXID 150mg (one in the morning, one at night).Then I started having Gastroesophageal reflux, mostly at night. My doctor prescribed AXID 300mg (once a day) and PREPULSID 10mg (or propulsid)to take 1/2 hour before meals. I'm also taking synthroid .125 mg daily. Are there any major adverse effects or contraindications with the combination of these three drugs? How do Axid and Prepulsid work together or what are they supposed to be doing? How do I know if I'm allergic to them? I'm 29 years old and besides my gastric problems and hypothyroid (treated since age 2), I'm healthy.

Answer: Do you need group rates for these questions? I think you need to establish a relationship with a physician that you trust and that can help you with your marked anxiety about your health. Anyway, regarding Axid and Propulsid. Axid decreases acid by blocking the H2 receptor in the gastric mucosa. Propulsid works by helping the motility of the GI tract and thus preventing reflux. Axid doesn't prevent reflux-just makes it less acid and less damaging to your esophagus. We combine these two drugs all the time with no apparent problem.

Gastroesophageal Reflux
Question: I felt a chest pain above my left breast two weeks ago. It later turned into a really bad heartburn. The heartburn got better with Axid 150mg my doctor prescribed. But then, I started having Gastroesophageal reflux, mostly at night for the past week. As it happens, my throat feels like it's on fire, that there's a lump in my throat. I cough. My nose goes from being congested to being clear. Later that day, as I'm walking or doing any physical activity it feels like I have difficulty breathing normally, like an asthmatic even though I have never been asthmatic in my life. I want to know how much damage can acid do to my lungs, throat, ears, vocal chords, or anything else like my teeth, I find they don't look and feel the same. How many reflux episodes can my body take? Is my heart pumping all this acid too? I went to see my doctor today and she wrote me a prescription for Axid 300mg and Prepulsid 10 mg. Will they work right away? or will I have to go through another night in Hell! Also, do these drugs heal or they just relieve the symptoms?

Answer: They both heal and prevent problems pertaining to acid-depending on the cause of the original problem.

Chemical Structure
Question: What is the chemical structure and name of this medicine and its usage, its side effects, and its better substitutes.

Answer: Axid(nizatidine) belongs to the class of drugs called H2 Blockers. This class includes Tagamet, Pepcid, Zantac, etc. It is one of the later developed drugs of the class. It is used to block stomach acid and to treat ulcers, acid reflux, etc. It is extremely well tolerated(hence why the class is available over the counter without prescription) the most common side effects are headache, abdominal pain, diarrhea and rhinitis.
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