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Doctors' Answers to "Frequently Asked Questions" - Acetaminophen
Related Info: Aspirin, Aleve
Acetaminophen Maximun Dosage [posted 11/3/98]
Answer: The daily limit of acetaminophen varies by weight and size. Some patients will experinece liver toxicity at lower doses than others. 10-15 gms can be hepatoxic and greater than 20 gm are potentially fatal. We usually don't recommend more than 3 gm a day. Higher sustained doses would require occasional liver function tests. Your tolerance to acetaminophen does not change. Your tolerance and ability to handle narcotics does. If you need more pain relief, increase the narcotics, not the acetaminophen.
Aspirin & Tylenol Dangers [posted 10/13/98]
Answer: Any analgesia-aspirin, acetaminophen, nsaids will cause decreased renal function if taken long term. This usually means 6 or more a day for at least 10 years. Smaller doses for shorter times may have an effect;but, too difficult to measure currently.