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Doctors' Answers to "Frequently Asked Questions" - Wenger's Granulomatosis
Answer: Wegener's Granulomatosis is one of those diseases that is hard to classify. Currently, there is no known cause. The body tends to produce "non-caseating granulomas" which are inflammatory nodules in different organs. These can become large enough to be interpreted as cancer on a CAT scan-but, they are not. They are most commonly seen in the sinuses and the lungs;but, can affect most of the other internal organs. The disease is usually classified as a vasculitis meaning inflammation of the blood vessels. It can be indolent or progress rapidly to death. It is usually treated with drugs such as cytoxan and steroids with complete remission seen in 70-80% with this regimen.