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Doctors' Answers to "Frequently Asked Questions" - Subclavian Vein Thrombosis


These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

Subclavian Vein Thrombosis
Question: Are there any records of subclavian vein thrombosis being caused by an infusion of doxycycline? How long does it take for someone to get back to normal after such an incident?

Answer: Doxycycline is an antibiotic related to the tetracycline family of drugs. These drugs are very effective antibiotics, but tend to be very inflammatory. This class of drugs is often used with patients with recurrent pulmonary effusions to inflame and scar the pleura - thus causing the lung lining(pleura) to adhere to the chest wall. However, the use of any substance intravenously can produce inflammation and subsequent clotting or sclerosis. Once a clot forms it may be a permanent thing. Generally, if the vein does not open after one or two weeks it will not usually return to normal.

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