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Doctors' Answers to "Frequently Asked Questions" - Hormone Therapy
Related Women's Issues
Considering Cardiac Risks of Premarin
Use [posted 11/5/98]
Answer: There may be a slightly increased risk for the first year of use, then the risk drops. Most physicians would strongly recommend estrogen use to decrease vascular disease.
Bellamine S tablets for Menopausal
Symptoms [posted 11/4/98]
Answer: As to the history, I would contact the company, a list of numbers is in the front of the PDR. Side effects are usually constipation and dry mouth. This class of drugs was used extensively in the 60s and 70s;but, stopped due to law suits as I recall. There were few actual problems, just legal ones.
Premarin Concerns [posted
Answer: The best current drug to decrease cardiovascular disease is estrogen. Women still die most frequently from this class of problems, not cancer or other problems. A very good study was done on nurses which showed both an increase in longevity and an increase in quality of life in women taking estrogen. If there is a strong family history of breast cancer it should probably be avoided and reloxafene taken instead. For a women who has elevated cholesterol, this would be one of the best drugs going from my prospective. As to natural estrogens, there is no direct evidence that there is any difference in your body's response. Nature must have intended for us to have elevated blood pressure and diabetes mellitus;but, we treat these with increased longevity. Your call, but, a great drug for longevity and quality of life.
DepoLupron & Hormone Production
Answer: DepoLupron is a synthetic nonapeptide analong of gonadotropin-releasing hormone. It works as an LH-RH agonist inhibiting sexual hormone production. In this manner, it effectively decreases or stops natural production of testerone(in men the usual receptors ). Side effects center on those seen with steroid absence-similar to what women experience in menopause. Hot flashes, decreased sexual drive, impotence, difficulty concentrating, weakness etc.
Finding Plant Based Alternative to
the Animal Based Premarin
Answer: Opposed due to what? Estropipate is made by Ortho/McNeil and is stucturally different from other types of estrogen. However, seems to have the same risks/benefits of the other estrogens. These include hypercoagubility, hypertension, cancer of the breast and uterus, and fluid retention. There are no major differences in side effects between Premarin and Estropipate.
Hormone Replacement Therapy
Answer: It sounds like you have just recently started taking hormonal replacement. Usually, Prempro will not cause spotting, one of the reasons for its popularity. However, the spotting represents build up of your endometrium and may require a burst of progesterone to cause a regular period. I'd give it two or three more weeks to see if it goes away. If not, you will probably need a regular cycle or switch to an estrogen regimen followed by a progesterone burst (causing regular periods).
Answer: Sure. Double the dose and see if it vanishes. If not, get a complete
workup by a good internist.
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