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Doctors' Answers to "Frequently Asked Questions" - Cyclophosphamide
Answer: Cyclophosphamide can lead to sterility depending on the person and the dosage. The amount of time that the drug is given also has an effect as does the patients age. If the drug will be given for an extended time at high doses, many physicians recommend that eggs be harvested and frozen to ensure future fertility. This is expensive and may not be necessary; but, is the only sure protection.